What Is Wellbutrin?
Wellbutrin is the brand name for the dopamine and noradrenalin reuptake inhibitor antidepressant bupropion. It is commonly prescribed with Lexapro, as their complementary antidepressant mechanisms [1, 2].
Wellbutrin increases the availability of dopamine and noradrenalin in the central nervous system. Dopamine is an important neurotransmitter for reward and movement. In contrast, noradrenalin is the key molecule for arousal, a component of the sympathetic and parasympathetic nervous system and increases prefrontal cortex activity [3].
Due to this function, Wellbutrin is superior to other antidepressants in improving cognitive function. This was demonstrated through patients, who initially had low mental processing speed and visual memory, showing improvement in these functions after taking 150mg/day of sustained release Wellbutrin (Wellbutrin XL) [1]. These effects can also generalize to Wellbutrin SR, the faster releasing form of Wellbutrin [4].
Wellbutrin Brain Fog: What Is It?
What Is Brain Fog?
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